Software - CSibelia

You have assembled the genomes, that's great!

C-Sibelia will help you in the next step: Comparing assemblies to a reference genome. As a result, you will get:

  • A VCF file that describes all the found variants
  • A circos picture visualizes all rearrangements

For your convenience, C-Sibelia also annotates and predicts the effects of these variants on genes using snpEff.

Here is a Short Introduction Video to C-Sibelia 

News: C-Sibelia is published in F1000Research.

If you use C-Sibelia, please cite: Minkin I, Pham H, Starostina E, Nikolay Vyahhi, and Son Pham (2013) "C-Sibelia: an easy-to-use and highly accurate tool for bacterial genome comparison", F1000Research 2013, 2:258.


You can try using C-Sibelia with these assembly and reference files 

Use Online Tool

If you have questions or need further support, please contact Son Pham or us.

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